While we're still waiting for an official localized release of Nintendo's Mother 3 outside of Japan (that's EarthBound 2 to you and me, and of course the fans took care of the unofficial release a few years ago), apparently there's still a push from the fans for designer Shigesato Itoi to lead a new team to develop Mother 4.  Don't hold your breath though; Itoi says that such a thing is impossible.  Kotaku translates an interview from Game Watch Impress:

Here’s how Itoi explained his thinking. “Among big-time popstars, if they, you know, put out ten albums, around the fourth album, they can’t make very good songs. The albums sell, but everyone at the concerts wants to hear songs from those first three albums. Everyone.” 

“I’m glad that video games are not my profession,” said Itoi, who’s best known in Japan as a copywriter and a commentator. “If it was my job, I would’ve already made 4 and 5.”

As much as I'd love more EarthBound and would want to see more of it, if Itoi is uncomfortable with creating additional sequels, I'm ready to let it go.  Let's enjoy the games we have with their stirring stories and emotional themes rather than drive the franchise into the ground with soulless sequels.